In the year 1988, the Department of Pharmaceutical Chemistry at KLE College of Pharmacy, Belagavi, was established. “In the Department of Pharmaceutical Chemistry, we synthesize/isolate and explore molecules of therapeutic relevance for better health, empowered by novel technologies at the interface of chemistry, analysis, and computational sciences.”
The department has adequate well-trained, enthusiastic faculty members with ample experience. Our academic members have a variety of specialties, including analytical, synthetic, and natural chemistry. We develop the next generation of pharmaceutical chemists through our extensive educational programs, giving them the know-how and abilities to succeed in academia, business, and research. Students participate in practical laboratory activities, become proficient in cutting-edge technology, and obtain a thorough understanding of the drug development process.
The Department of Pharmaceutical Chemistry takes great pleasure in its dedication to giving students a comprehensive and enriching educational experience. To accomplish this, we routinely plan a number of workshops, seminars, and guest lectures that explore the latest developments in pharmaceutical sciences. These platforms provide opportunities for students and scholars to interact with industry experts, exchange ideas, and stay updated on emerging trends.
Key features:
· Pharmaceutical chemistry thrives on the broad goals of drug discovery and optimization of new chemical entities suitable for therapeutic use.
· Our research apprehends the biological roles of drugs, proteins & cellular design, and their structure-activity relationships (SAR) along their ADME properties to apply these principles for the therapeutic benefit of patients.
· For this, our department offers a wide area of research in new drug discovery processes to probe new biomolecules; novel and better ways to enhance their therapeutic efficacy.
· We also create and continually refine the quality aspects of bioactive and drug formulations through the process and development of new analytical methods and bioanalytical fluids with the aim of ensuring efficacy, fitness, and stability.
· Computer-aided drug design and new biotechnological approaches are opening new avenues in the field of medicinal chemistry.
Strength of Department:
The Department of Pharmaceutical Chemistry is a dynamic and pivotal academic unit within the realm of pharmaceutical sciences. With an unwavering commitment to advancing drug discovery, development, and design, the department plays a crucial role in bridging the gap between chemistry and medicine.
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Synthetic Drug Discovery of new chemical entities.
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Exploring bioactives from natural sources. Novel Analytical Method Development for new drugs in dosage forms and biological fluids.
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In-silico drug designs (Schrodinger, ChemOffice).
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Drug Polymorphism Studies.
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Isolation and purification of drug molecules from synthetic and natural sources using Chromatographic techniques – HPLC, HPTLC, Flash.
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Anticancer, Antitubercular, antiviral, antimicrobial, anti-diabetic, and anti-inflammatory management studies.
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Pharmacokinetics studies for drug design
CAREER OPPORTUNITIES IN PHARMACEUTICAL CHEMISTRYPharmaceutical Bulk Drug Division
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Drug Discovery & Development
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Pharmaceutical Analytical R & D
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Quality Control & Quality Assurance Division
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Pharmaceutical Manufacturing Division
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Marketing and Medicinal Detailing Division
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Intellectual Property Rights Division
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Formulation & Development Division
THURST AREAS OF THE DEPARTMENT:
Medicinal Chemistry and Drug Design:
Developing new compounds with therapeutic potential, optimizing their properties, and designing molecules that interact effectively with biological targets.
Computational Chemistry:
The use of computational modelling and simulation tools to anticipate chemical interactions, analyze binding affinities, and accelerate drug discovery.
Natural Products and Herbal Medicine:
Exploring the chemical composition of natural products, studying their pharmacological activities, and identifying potential leads for drug development.
Analytical Techniques and Quality Control:
Developing advanced analytical methods to quantify drug compounds, detect impurities, and ensure the quality and safety of pharmaceutical products.
Nanoparticle synthesis: Nanoparticle synthesis using plant extracts explores green synthesis methods for creating functional nanoparticles with potential applications in medicine.
Polymorphism study: investigates multiple crystalline structures of the substance, impacting properties and applications. Understanding these variations aids material design and pharmaceutical development.
Publications for last 5 years: 60
Indexed: 44
Non-Indexed: 16
Impact factor: 0.2-5.29
Published Books: 03
Patents: 04
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Name of the faculty
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Title
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Patent ID
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Date of publication
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Dr. Preeti Salve
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Quercetin loaded eudrgit S100/gm nanoparticles for antidiabetic use
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202221043000 A
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12/08/2022
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Dr. Preeti Salve
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Curcumin-loaded solid lipid nanoparticles for anti-inflammatory use
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202221043410 A
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12/08/2022
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Ms. Rohini Kavalapure
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Process for synthesis of pyrazole-methoxyphenyl derivatives and isolates with anti-inflammatory activity
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202211069330
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09/12/2022
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Ms. Rohini Kavalapure
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Process for synthesis 1,2,4-Triazole derivatives with anti-cancer activity
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202311006681
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10/02/2023
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Research and Development (R&D) Scientist: Work in pharmaceutical companies to develop new drug compounds, and conduct laboratory experiments. You may focus on areas like synthesis, formulation development, analytical chemistry, and quality control.
Medicinal Chemist: Discovery and synthesis of novel chemicals with potential medicinal applications as a specialty. By developing compounds with desired interactions with biological targets, medicinal chemists contribute to the discovery and development of new drugs.
Analytical Scientist: Focus on examining the physical and chemical characteristics of medicinal molecules. This function is essential to quality control because it guarantees the reliability and security of drug goods.
Quality Control and Assurance: Pharmaceutical product quality is monitored and upheld by quality control and assurance. Professionals in quality control make sure that products comply with industry standards and meet specifications.
Pharmaceutical Consultant: Offer your expertise to pharmaceutical companies on specific projects, such as drug development strategies, and quality improvement.
Intellectual Property Specialist: Analyse and evaluate patent applications related to pharmaceutical innovations. Intellectual property specialists help protect and manage intellectual property rights.
Academic and Research Positions: Pursue a career in academia by becoming a lecturer, assistant professor, or researcher in universities and research institutions. You can contribute to advancing scientific knowledge and training future professionals.
Entrepreneurship: With the correct set of skills and experience, you can launch your own pharmaceutical-related company, such as a contract research organization (CRO), consultancy firm, or biotechnology startup.
Instruments available in the department:
HPLC: Waters Alliance e2695 separation module, equipped with PDA detector
FTIR: Shimadzu IR affinity-1
DSC: shimadazu DSC-60
UV: Shimadzu UV 800
Digital Ultrasonic Cleaner
Distillation unit
Hot air oven
Buchi Rotavapor R-210
Magnetic stirrer (REMI Equipment's, IKA-MAG-HA-7)
Superfit UV cabinet
Sartorius electronic balance (BSA822)
Awards and achievements:
Best Scientist Award: Dr. Shankar. G. Alegaon
Young Scientist Award: Dr. Preeti Salve
Young Researcher Award by Career Point School of Pharmacy, Kota, Rajasthan: Mr. S. S. Suryawanshi
Best oral presentation at JSS College of Pharmacy, Ooty, The Nilgiris, Tamil Nadu: Ms. Rohini Kavalapure
Best poster presentation: Mr. S. S. Suryawanshi
Best PhD thesis award by KAHER 2022: Dr. Preeti Salve
Dr. P. D. Patil, Best thesis award 2023: Shankar Gharge
